The chronic use of pantoprazole has caused stomach cancer in animal studies, but it is not known if this medication would have the same effects in humans. Following healing of gastric or duodenal ulcers with pantoprazole treatment, elevated apotheke pantoprazole gastrin levels return to normal by at least months. Source:MedicineNet Gastroesophageal Reflux Disease GERD, Heartburn Learn about gastroesophageal reflux disease GERD, acid reflux, heartburn symptoms like hearbrun, chest pain, regurgitation, and nausea. To address related issue that has raised questions about the PPI clopidogrel interaction, the researchers also looked at whether or not PPIs independently increase the risk of CV event.