Ezetimibe marketed as Zetia or Ezetrol hailed as the new genera-tion of cholesterol-lowering drug, supposedly works by inhibiting chol-esterol uptake in the small intestine, unlike statins, which inhibit the absorption of cholesterol in the liver. Fibrates The efficacy and safety of co-administration of ezetimibe with fibrates other than fenofibrate have not been studied. waar te koop zetia door kabeljauw In the meantime, some doctors say, they must essentially take on faith that Zetia cholesterol-lowering ability will translate into real-world benefits and that its long-term use with statins does not have major risks. Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels 4,. Zetia targets protein called NPC1L1, in both the liver and the intestines. Food and Drug Administration FDA to sell its cholesterol fighting ezetimibe in the United States.