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The possibility that the patient may have taken other drugs as well as SINEMET CR should be taken into consideration. The addition of kaufen gunstigsten sinemet carbidopa in 1:10 ratio with levodopa increases the dose at which significant proportion of mice are expected to die to 3360 mg kg. Seek immediate medical attention if any of these rare but very serious side effects occur: fast shallow breathing, confusion, severe dizziness fainting, high fever, unusual muscle stiffness, unusual sweating. Subscribe to our popular newsletter containing regular roundup of medication news, alerts and new drug approvals.