Use second non-hormone method of birth control such as condom, diaphragm, spermicide to prevent pregnancy while taking amoxicillin and clavulanate potassium. Should receive 500 mg or 250 mg every 12 hours, depending on the severity of the infection. Neither component in amoxicillin clavulanate potassium is highly clavulanic acid has been found to be approximately 25 bound to human serum and amoxicillin approximately 18 bound. It is important to take Amoxicillin and clavulanate regularly to get the most benefit. This drug is known to be substantially excreted by the kidney, and the online prescription clavulanate risk of dose-dependent toxic reactions to this drug may be greater in patients with impaired renal function. The results of experiments involving the administration of clavulanic acid to animals suggest that this compound, like amoxicillin, is well distributed in body tissues. Comparable efficacy was demonstrated between the q12h and q8h dosing regimens.